High Mortality Unaffected by Age, Gender and Steroid use is the Hallmark of  COVID-19 in Diabetes:-

Observations from a Retrospective Analysis during Peak of 2020 Pandemic in India 


The present retrospective study aimed to determine the severity of COVID-19 and outcomes un patients of diabetes admitted with COVID-19 . 


Records of admitted COVID-19 patients suffering from diabetes or having  admission  hyperglycaemia (random plasma glucose >= 200mg/dl) between March to August 2020 were analysed for severity and outcomes of COVID-19, presence of comorbidities, steroid use and correlated with hyperglycaemia.


COVID-19 patients (severe disease - 35, moderate-43.5%and severe-72.7%). Mortality was similar across age and gender. Prevalence of comorbidities was similar in survivors (20.6%)and non-survivors (24.3%) . Newly detected hyperglycaemia at admission was noted in 9 patients, two -thirds of which had severe COVID-19 AND 5 EXPIRED (55.5%) , higher callus of plasma glucose at admission (295.9 vs 236.4 mg/dl, p=0.047) and high fasting plasma glucose values (210.3 vs 166.5 mg/dl, p=0.043) were observed among non-survivors , Mortality rates were statistically similar in those who received steroids and those who did not .


COVID-19 IN DIABETES PATIENTS REQUIRING ADMISSION CARRIES HIGH MORTALITY IRRRESPECTIVE OF AGGE , GENDER, PRESENCE OF COMORBIDITIES AND STEROID USE , HOWERER , ADMISSION HYPERGLYCEMIA AND HOGH FASTING PLASMA GLUCOSE VALUES ARE ASSOCIATED WITH HOGHER MORTALITY .









References- 


GDB 2017 Disease and injury incidence and prevalence Collaborators , Global , regional and national incidence prevalence and years lived with disability for 354 diseases and injuries for 195 countries and territories , 1990-2017 ; a systematic analysis for the Global Burden of Disease Study 2017. lancet 2018 ; 392:1789-1858


Chen Y , Yang D, Cheng B , Chen J, Peng A, Yang C, et al Clinical  characteristics and outcomes of patients with diabetes and COVID -19 in association with glucose-lowering medication  Diabetes Care 2020; 43:1399-1407